One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

HIGHLIGHTS Many AD target combinations are being explored for multi-target drug design.New databases and models increase the potential of computational drug designLiraglutide and other antidiabetics are strong candidates for repurposing to AD.Donecopride a dual 5-HT/AChE inhibitor shows promise in pre-clinical studies Alzheimer's Disease is a complex and multifactorial disease for which the mec...

One for all, all for one: Agents with social identities

One of the challenges in developing multi-agent systems is the creation of agents able to exhibit human-like behaviours in complex social situations. In order to do so, agents need to be socially aware of their environment and perceive other agents not only as individuals but also as social group members. Following Social Identity and Self-Categorization theories, we developed the Dynamic Ident...

All for One, One for All

When we attend library conferences we often rush back to our libraries excited to implement some of the ideas that we’ve heard. Lucy Lockley presented a session at the 2012 Public Library Association Conference that focused on a staffwide, all-inclusive readers’ advisory model. With an “all for one, one for all” mentality, we receive a vision for including all staff in readers’ advisory service...

One for all; all for one.

I want to thank the entire Xavier community for the opportunity to have served as your interim provost over the past year. Returning to a Jesuit environment I’d not experienced since high school was even more satisfying than I could have anticipated. The way that Ignatian values permeate this culture and are practiced by nearly everyone distinguishes you in ways that others can’t even imagine. ...

One disease, multiple manifestations.